丁苯酞治疗急性缺血性脑卒中的药物经济学研究.docx

《丁苯酞治疗急性缺血性脑卒中的药物经济学研究.docx》由会员分享，可在线阅读，更多相关《丁苯酞治疗急性缺血性脑卒中的药物经济学研究.docx（10页珍藏版）》请在第一文库网上搜索。

1、丁苯猷治疗急性缺血性脑卒中的药物经济学研究章建权汤周荣陈伟俊表1两组干预前及干预15 d后NIHSS评分比较（5土 s）组别干预前 干预15 d后 值 。值观察组(n=50 )8.1 0.3对照组(=50 )8.0 0.3I 值1.667P 值0.0994.3 0.184.9710.0005.5 0.249.0290.00037.9470.000表2两组治疗成本比较元,（x5）组别检查及化彩费护理及床位费药物治疗费总成本观察组（n=50 ）3 869.5 125.71 356.8 28.94 378.9 56.89 605.2 98.6*授艮组(n=50 )4 861.9 204.81 535

2、.7 37.48 958.7 231.715 3563 196.4，值29.20326.764135.749185.048Ptti0.0000.0000.0000.000表3两组不良反应发生情况比较例（）组别头吊目眩消化道不适乏力肝功能损伤合计观察组（n=50）1 ( 2.0 )001 ( 2.0)2 (4.0)对照组（n=50）3 ( 6.0 )4 ( 8.0 )2 (4.0)5 ( 10.0)14 ( 28.0)Summary目的：探官寸丁苯猷治疗急性缺血性脑卒中的药物经济学价值。方法：选择2018年7月-2019年12月本院收治的100例急性缺血性脑卒中患者，根据随机数字表法将其分为观察

3、组和对照组，每组50例。对照组使用基础治疗，观察组在对照组的基础上加用丁苯猷。比较两组治疗成本、临床有效率、成本-效益比、不良反应发生情况及干预前和干预15 d后的NIHSS评分。结果：干预前，两组NIHSS评分比较，差异无统计学意义(P0. 05)；干预15d后，两组NIHSS评分均低于干预前，且观察组低于对照组，差异均有统计学意义(P0.05) o观察组检查及化验费、护理及床位费、药物治疗费、总成本均低于对照组，差异均有统计学意义(P0.05) o观察组有效率高于对照组，差异有统计学意义(P0.05) o观察组成本-效益比低于对照组，差异有统计学意义(P0.05) o观察组不良反应发生率低

4、于对照组，差异有统计学意义(P0. 05) ； after 15 d of intervention, NIHSS scores of bothgroups were lower than before intervention, and that of observationgroup was lower than that of control group, the differences werestatistically significant (P0. 05) . The examination and laboratorycosts, nursing and bed costs,

5、drug treatment costs and total costsof observation group were lower than those of control group, and thedifferences were statistically significant (P0, 05) . The effectiverate of observation group was higher than that of control group, thedifference was statistically significant (P0. 05) . The cost-

6、benefitratio was lower than that of control group, the difference wasstatistically significant (P0.05) . The incidence of adversereactions of observation group was lower than that of control group,the difference was statistically significant (P0.05),具有可比性。2.2 雨组干预前及干预15 d后NIHSS评分比较 干预前，两组NIHSS评分比较，差异无统